Given that the ooofbot (out-of-office auto reply robot) varies from
system to system, and there is no telling which address the blasted
things are going to respond to, even if the person properly installs
the version he has access to for his system, it is a listowner problem.
(Hey, if Eric wanted it to be totally automatic he wouldn't have invented
listowners!  ;-)  )

ooofs can go three ways
 1) to the owner-listname address as an error
 2) to the person who posted the original item to the list
 3) to the list itself (the nastiest, can cause mail-loops, and a lot
    of upset subscribers, and can take a long time to untangle the knot)

Only way I know to deal with it is beg subscribers to please set nomail
or unsub before invoking an ooofbot (kinda like begging they not
overqoute), explain to them how it works (if your posting to the list
resulted in an ooofbot from one address, please tell the listowner(s)
so it can be dealt with, etc.).

Beside the ooofbot problem, you also have return-reciept, confirm-opening,
etc. to deal with, as listowner.  You didn't step through the looking
glass, or fall down a rabbit hole, or get whisked away by a tornado,
you simply became a listowner, which often means you are a little of
everything (yeah, I took several psych. classes in college, but I ain't
got no license to practice).  And remember, listowners can't win; they
must know everything (if they don't they're incompetent) but not say it
(autocratic, pedantic, overbearing, you-name-it, an them's the mild ones).
You gotta take it not only from the subscribers but also from the
administrators of the sites where your subscribers are when you are trying
to get a problem fixed.

So, a few grey hairs.  If the list is worth it, it's worth it.

Douglas